Tumor-associated macrophages in oral premalignant lesions coexpress CD163 and STAT1 in a Th1-dominated microenvironment

BACKGROUND: Tumor-associated macrophages (TAMs) are implicated in the growth, invasion and metastasis of various solid tumors. However, the phenotype of TAMs in premalignant lesions of solid tumors has not been clarified. In the present study, we identify the phenotype of TAMs in leukoplakia, an ora...

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Udgivet i:BMC Cancer
Main Authors: Mori, Kazumasa, Haraguchi, Shigeki, Hiori, Miki, Shimada, Jun, Ohmori, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525742/
https://ncbi.nlm.nih.gov/pubmed/26242181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1587-0
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