Tumor-associated macrophages in oral premalignant lesions coexpress CD163 and STAT1 in a Th1-dominated microenvironment

BACKGROUND: Tumor-associated macrophages (TAMs) are implicated in the growth, invasion and metastasis of various solid tumors. However, the phenotype of TAMs in premalignant lesions of solid tumors has not been clarified. In the present study, we identify the phenotype of TAMs in leukoplakia, an ora...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Mori, Kazumasa, Haraguchi, Shigeki, Hiori, Miki, Shimada, Jun, Ohmori, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525742/
https://ncbi.nlm.nih.gov/pubmed/26242181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1587-0
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