Tumor-associated macrophages in oral premalignant lesions coexpress CD163 and STAT1 in a Th1-dominated microenvironment

BACKGROUND: Tumor-associated macrophages (TAMs) are implicated in the growth, invasion and metastasis of various solid tumors. However, the phenotype of TAMs in premalignant lesions of solid tumors has not been clarified. In the present study, we identify the phenotype of TAMs in leukoplakia, an ora...

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Publicado en:BMC Cancer
Autores principales: Mori, Kazumasa, Haraguchi, Shigeki, Hiori, Miki, Shimada, Jun, Ohmori, Yoshihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4525742/
https://ncbi.nlm.nih.gov/pubmed/26242181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1587-0
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