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Mechanisms of Resistance to Interferon-γ-mediated Cell Growth Arrest in Human Oral Squamous Carcinoma Cells

Interferon-γ (IFNγ) has an antiproliferative effect on a variety of tumor cells. However, many tumor cells resist treatment with IFNs. Here, we show that IFNγ fails to inhibit the growth of some types of oral squamous cell carcinoma (OSCC) cells that possess a fully functional IFNγ/STAT1 (signal tra...

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Detalhes bibliográficos
Main Authors: Hiroi, Miki, Mori, Kazumasa, Sekine, Keisuke, Sakaeda, Yoshiichi, Shimada, Jun, Ohmori, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757190/
https://ncbi.nlm.nih.gov/pubmed/19596857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.025932
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