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Role of IFN-γ in induction of Foxp3 and conversion of CD4(+) CD25(–) T cells to CD4(+) Tregs
IFN-γ is an important Th1 proinflammatory cytokine and has a paradoxical effect on EAE in which disease susceptibility is unexpectedly heightened in IFN-γ–deficient mice. In this study, we provide what we believe is new evidence indicating that IFN-γ is critically required for the conversion of CD4(...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1533873/ https://ncbi.nlm.nih.gov/pubmed/16906223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25826 |
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