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Induction of CD4(+)CD25(+) regulatory T cells by copolymer-I through activation of transcription factor Foxp3
Copolymer-I (COP-I) has unique immune regulatory properties and is a treatment option for multiple sclerosis (MS). This study revealed that COP-I induced the conversion of peripheral CD4(+)CD25(-) to CD4(+)CD25(+) regulatory T cells through the activation of transcription factor Foxp3. COP-I treatme...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088385/ https://ncbi.nlm.nih.gov/pubmed/15851684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502187102 |
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