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Induction of CD4(+)CD25(+) regulatory T cells by copolymer-I through activation of transcription factor Foxp3

Copolymer-I (COP-I) has unique immune regulatory properties and is a treatment option for multiple sclerosis (MS). This study revealed that COP-I induced the conversion of peripheral CD4(+)CD25(-) to CD4(+)CD25(+) regulatory T cells through the activation of transcription factor Foxp3. COP-I treatme...

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Détails bibliographiques
Auteurs principaux: Hong, Jian, Li, Ningli, Zhang, Xuejun, Zheng, Biao, Zhang, Jingwu Z.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088385/
https://ncbi.nlm.nih.gov/pubmed/15851684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502187102
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