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Functional defects in CD4(+) CD25(high) FoxP3(+) regulatory cells in ankylosing spondylitis
Forkhead box P3 (FoxP3)-positive regulatory T cells (Tregs) play a pivotal role in the preservation of self-tolerance, and Treg dysfunction has been implicated in many autoimmune diseases. Whether and how Tregs participate in the pathogenesis of ankylosing spondylitis (AS) has not been fully elucida...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5128857/ https://ncbi.nlm.nih.gov/pubmed/27901054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37559 |
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