Hepatitis B envelope antigen increases Tregs by converting CD4+CD25(-) T cells into CD4(+)CD25(+)Foxp3(+) Tregs

Hepatitis B virus (HBV) can establish a lifelong chronic infection in humans, leading to liver cirrhosis, liver failure and hepatocellular carcinoma. Patients with chronic hepatitis B (CHB) exhibit a weak virus-specific immune response. Regulatory T cells (Tregs) play a key role in regulating the im...

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Bibliographic Details
Published in:Exp Ther Med
Main Authors: Tang, Rui, Lei, Zhigang, Wang, Xinpeng, Qi, Qianqian, He, Jingjing, Liu, Dan, Wang, Xiaoxian, Chen, Xiaojun, Zhu, Jifeng, Li, Yalin, Zhou, Sha, Su, Chuan
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444405/
https://ncbi.nlm.nih.gov/pubmed/32855720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9107
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