SjHSP60 induces CD4(+)CD25(+)Foxp3(+) Tregs via TLR4-Mal-drived production of TGF-β in macrophages

CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) play a pivotal role in limiting immunopathological damage to host organs after schistosome infection. Transforming growth factor-β (TGF-β) is an essential factor for the periphery conversion of CD4(+)CD25(−) T cells into CD4(+)CD25(+)Foxp3(+) Tregs by...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Zhou, Sha, Qi, Qianqian, Wang, Xiaofan, Zhang, Lina, Xu, Lei, Dong, Liyang, Zhu, Jifeng, Li, Yalin, Wang, Xuefeng, Xu, Zhipeng, Liu, Feng, Hu, Wei, Zhou, Liang, Chen, Xiaojun, Su, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197892/
https://ncbi.nlm.nih.gov/pubmed/29697865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12160
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