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β(1)-adrenergic receptor N-terminal cleavage by ADAM17; the mechanism for redox-dependent downregulation of cardiomyocyte β(1)-adrenergic receptors
β(1)-adrenergic receptors (β(1)ARs) are the principle mediators of catecholamine action in cardiomyocytes. We previously showed that the β(1)AR extracellular N-terminus is a target for post-translational modifications that impact on signaling responses. Specifically, we showed that the β(1)AR N-term...
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| Publicado en: | J Mol Cell Cardiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8068644/ https://ncbi.nlm.nih.gov/pubmed/33556394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2021.01.012 |
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