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β(1)-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes
β(1)-adrenergic receptors (β(1)ARs) mediate catecholamine actions in cardiomyocytes by coupling to both Gs/cAMP-dependent and Gs-independent/growth-regulatory pathways. Structural studies of the β(1)AR define ligand-binding sites in the transmembrane helices and effector docking sites at the intrace...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554155/ https://ncbi.nlm.nih.gov/pubmed/28801655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06607-z |
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