β(1)-adrenergic receptor O-glycosylation regulates N-terminal cleavage and signaling responses in cardiomyocytes

by Park, Misun, Reddy, Gopireddy R., Wallukat, Gerd, Xiang, Yang K., Steinberg, Susan F.
Published in Sci Rep (2017)

β-Adrenergic control of sarcolemmal Ca(V)1.2 abundance by small GTPase Rab proteins

by del Villar, Silvia G., Voelker, Taylor L., Westhoff, Maartje, Reddy, Gopireddy R., Spooner, Heather C., Navedo, Manuel F., Dickson, Eamonn J., Dixon, Rose E.
Published in Proc Natl Acad Sci U S A (2021)

Phosphodiesterase 5 Associates With β2 Adrenergic Receptor to Modulate Cardiac Function in Type 2 Diabetic Hearts

by West, Toni M., Wang, Qingtong, Deng, Bingqing, Zhang, Yu, Barbagallo, Federica, Reddy, Gopireddy R., Chen, Dana, Phan, Kyle S., Xu, Bing, Isidori, Andres, Xiang, Yang K.
Published in J Am Heart Assoc (2019)

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure

by Barbagallo, Federica, Xu, Bing, Reddy, Gopireddy R., West, Toni, Wang, Qingtong, Fu, Qin, Li, Minghui, Shi, Qian, Ginsburg, Kenneth S., Ferrier, William, Isidori, Andrea M., Naro, Fabio, Patel, Hemal H., Bossuyt, Julie, Bers, Donald, Xiang, Yang K.
Published in Circ Res (2016)

Adenylyl cyclase 5–generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

by Syed, Arsalan U., Reddy, Gopireddy R., Ghosh, Debapriya, Prada, Maria Paz, Nystoriak, Matthew A., Morotti, Stefano, Grandi, Eleonora, Sirish, Padmini, Chiamvimonvat, Nipavan, Hell, Johannes W., Santana, Luis F., Xiang, Yang K., Nieves-Cintrón, Madeline, Navedo, Manuel F.
Published in J Clin Invest (2019)

A G(s)-coupled purinergic receptor boosts Ca(2+) influx and vascular contractility during diabetic hyperglycemia

by Prada, Maria Paz, Syed, Arsalan U, Buonarati, Olivia R, Reddy, Gopireddy R, Nystoriak, Matthew A, Ghosh, Debapriya, Simó, Sergi, Sato, Daisuke, Sasse, Kent C, Ward, Sean M, Santana, Luis F, Xiang, Yang K, Hell, Johannes W, Nieves-Cintrón, Madeline, Navedo, Manuel F
Published in eLife (2019)

GRK5 Controls SAP97-Dependent Cardiotoxic β(1) Adrenergic Receptor-CaMKII Signaling in Heart Failure

by Xu, Bing, Li, Minghui, Wang, Ying, Zhao, Meimi, Morotti, Stefano, Shi, Qian, Wang, Qingtong, Barbagallo, Federica, Teoh, Jian-Peng, Reddy, Gopireddy R., Bayne, Elizabeth F., Liu, Yongming, Shen, Ao, Puglisi, Jose L., Ge, Ying, Li, Ji, Grandi, Eleonora, Nieves-Cintron, Madeline, Xiang, Yang K.
Published in Circ Res (2020)

AKAP5 complex facilitates purinergic modulation of vascular L-type Ca(2+) channel Ca(V)1.2

by Prada, Maria Paz, Syed, Arsalan U., Reddy, Gopireddy R., Martín-Aragón Baudel, Miguel, Flores-Tamez, Víctor A., Sasse, Kent C., Ward, Sean M., Sirish, Padmini, Chiamvimonvat, Nipavan, Bartels, Peter, Dickson, Eamonn J., Hell, Johannes W., Scott, John D., Santana, Luis F., Xiang, Yang K., Navedo, Manuel F., Nieves-Cintrón, Madeline
Published in Nat Commun (2020)

Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling

by Riehle, Christian, Weatherford, Eric T., Wende, Adam R., Jaishy, Bharat P., Seei, Alec W., McCarty, Nicholas S., Rech, Monika, Shi, Qian, Reddy, Gopireddy R., Kutschke, William J., Oliveira, Karen, Pires, Karla Maria, Anderson, Joshua C., Diakos, Nikolaos A., Weiss, Robert M., White, Morris F., Drakos, Stavros G., Xiang, Yang K., Abel, E. Dale
Published in JCI Insight (2020)