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β-Adrenergic control of sarcolemmal Ca(V)1.2 abundance by small GTPase Rab proteins
The number and activity of Ca(v)1.2 channels in the cardiomyocyte sarcolemma tunes the magnitude of Ca(2+)-induced Ca(2+) release and myocardial contraction. β-Adrenergic receptor (βAR) activation stimulates sarcolemmal insertion of Ca(V)1.2. This supplements the preexisting sarcolemmal Ca(V)1.2 pop...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7896340/ https://ncbi.nlm.nih.gov/pubmed/33558236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017937118 |
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