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Enhancement of the Recycling and Activation of β-Adrenergic Receptor by Rab4 GTPase in Cardiac Myocytes

We investigate the role of Rab4, a Ras-like small GTPase coordinating protein transport from the endosome to the plasma membrane, on the recycling and activation of endogenous β-adrenergic receptor (β-AR) in HL-1 cardiac myocytes in vitro and transgenic mouse hearts in vivo. β(1)-AR, the predominant...

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Detalhes bibliográficos
Main Authors: Filipeanu, Catalin M., Zhou, Fuguo, Lam, May L., Kerut, Kenneth E., Claycomb, William C., Wu, Guangyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735442/
https://ncbi.nlm.nih.gov/pubmed/16484224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M511460200
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