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Carvedilol Prevents Redox Inactivation of Cardiomyocyte Β(1)-Adrenergic Receptors
The mechanism that leads to a decrease in β(1)-adrenergic receptor (β(1)AR) expression in the failing heart remains uncertain. This study shows that cardiomyocyte β(1)AR expression and isoproterenol responsiveness decrease in response to oxidative stress. Studies of mechanisms show that the redox-de...
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| Publié dans: | JACC Basic Transl Sci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6116783/ https://ncbi.nlm.nih.gov/pubmed/30175276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.06.002 |
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