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Munc13 binds and recruits SNAP25 to chaperone SNARE complex assembly
Synaptic vesicle fusion is mediated by SNARE proteins - VAMP2 on the vesicle and Syntaxin-1/SNAP25 on the pre-synaptic membrane. Chaperones Munc18–1 and Munc13–1 co-operatively catalyze SNARE assembly via an intermediate ‘template’ complex containing Syntaxin-1 and VAMP2. How SNAP25 enters this reac...
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| Publicat a: | FEBS Lett |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8068094/ https://ncbi.nlm.nih.gov/pubmed/33222163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14006 |
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