Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins

Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are evolutionarily conserved machines that couple their folding/assembly to membrane fusion. However, it is unclear how these processes are regulated and function. To determine these mechanisms, we characterized the fold...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zorman, Sylvain, Rebane, Aleksander A, Ma, Lu, Yang, Guangcan, Molski, Matthew A, Coleman, Jeff, Pincet, Frederic, Rothman, James E, Zhang, Yongli
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2014
Schlagworte:
Biophysics and Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166003/
https://ncbi.nlm.nih.gov/pubmed/25180101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03348
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