Two Disease-Causing SNAP-25B Mutations Selectively Impair SNARE C-terminal Assembly

Synaptic exocytosis relies on assembly of three soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins into a parallel four-helix bundle to drive membrane fusion. SNARE assembly occurs by step-wise zippering of the vesicle-associated SNARE (v-SNARE) onto a binary SNARE comple...

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Detaylı Bibliyografya
Yayımlandı:J Mol Biol
Asıl Yazarlar: Rebane, Aleksander A., Wang, Bigeng, Ma, Lu, Qu, Hong, Coleman, Jeff, Krishnakumar, Shyam, Rothman, James E., Zhang, Yongli
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805579/
https://ncbi.nlm.nih.gov/pubmed/29056461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.012
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