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Two Disease-Causing SNAP-25B Mutations Selectively Impair SNARE C-terminal Assembly
Synaptic exocytosis relies on assembly of three soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins into a parallel four-helix bundle to drive membrane fusion. SNARE assembly occurs by step-wise zippering of the vesicle-associated SNARE (v-SNARE) onto a binary SNARE comple...
में बचाया:
| में प्रकाशित: | J Mol Biol |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5805579/ https://ncbi.nlm.nih.gov/pubmed/29056461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.012 |
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