Loading...

Structural basis for the clamping and Ca(2+) activation of SNARE-mediated fusion by synaptotagmin

Synapotagmin-1 (Syt1) interacts with both SNARE proteins and lipid membranes to synchronize neurotransmitter release to calcium (Ca(2+)) influx. Here we report the cryo-electron microscopy structure of the Syt1–SNARE complex on anionic-lipid containing membranes. Under resting conditions, the Syt1 C...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Grushin, Kirill, Wang, Jing, Coleman, Jeff, Rothman, James E., Sindelar, Charles V., Krishnakumar, Shyam S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546687/
https://ncbi.nlm.nih.gov/pubmed/31160571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10391-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!