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Synaptotagmin oligomers are necessary and can be sufficient to form a Ca(2+)‐sensitive fusion clamp
The buttressed‐ring hypothesis, supported by recent cryo‐electron tomography analysis of docked synaptic‐like vesicles in neuroendocrine cells, postulates that prefusion SNAREpins are stabilized and organized by Synaptotagmin (Syt) ring‐like oligomers. Here, we use a reconstituted single‐vesicle fus...
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6349546/ https://ncbi.nlm.nih.gov/pubmed/30570144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13317 |
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