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Hypothesis – buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission
Neural networks are optimized to detect temporal coincidence on the millisecond timescale. Here, we offer a synthetic hypothesis based on recent structural insights into SNAREs and the C2 domain proteins to explain how synaptic transmission can keep this pace. We suggest that an outer ring of up to...
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| Publicado no: | FEBS Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5698743/ https://ncbi.nlm.nih.gov/pubmed/28983915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12874 |
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