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Complexin Activates and Clamps SNAREpins by a Common Mechanism Involving an Intermediate Energetic State
The core mechanism of intracellular vesicle fusion consists of SNAREpin zippering between vesicular and target membranes. Recent studies indicate that the same SNARE-binding protein, Complexin (CPX), can act either as a facilitator or as an inhibitor of membrane fusion, giving rise to a major contro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736826/ https://ncbi.nlm.nih.gov/pubmed/21785413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2102 |
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