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Munc13 binds and recruits SNAP25 to chaperone SNARE complex assembly

Synaptic vesicle fusion is mediated by SNARE proteins - VAMP2 on the vesicle and Syntaxin-1/SNAP25 on the pre-synaptic membrane. Chaperones Munc18–1 and Munc13–1 co-operatively catalyze SNARE assembly via an intermediate ‘template’ complex containing Syntaxin-1 and VAMP2. How SNAP25 enters this reac...

詳細記述

保存先:
書誌詳細
出版年:FEBS Lett
主要な著者: Sundaram, R Venkat Kalyana, Jin, Huaizhou, Li, Feng, Shu, Tong, Coleman, Jeff, Yang, Jie, Pincet, Frederic, Zhang, Yongli, Rothman, James E., Krishnakumar, Shyam S.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068094/
https://ncbi.nlm.nih.gov/pubmed/33222163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.14006
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