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BH3 Mimetic Sensitivity of Colorectal Cancer Cell Lines in Correlation with Molecular Features Identifies Predictors of Response

Colorectal cancer (CRC) is a heterogeneous disease, which in part explains the differential response to chemotherapy observed in the clinic. BH3 mimetics, which target anti-apoptotic BCL-2 family members, have shown potential in the treatment of hematological malignancies and offer promise for the t...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Zhang, Le, Ramesh, Prashanthi, Steinmetz, Maxime, Medema, Jan Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067732/
https://ncbi.nlm.nih.gov/pubmed/33917026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083811
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