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Epigenetic Characteristics of Human Subtelomeres Vary in Cells Utilizing the Alternative Lengthening of Telomeres (ALT) Pathway

Most human cancers circumvent senescence by activating a telomere length maintenance mechanism, most commonly involving telomerase activation. A minority of cancers utilize the recombination-based alternative lengthening of telomeres (ALT) pathway. The exact requirements for unleashing normally repr...

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Pubblicato in:Life (Basel)
Autori principali: Toubiana, Shir, Tzur-Gilat, Aya, Selig, Sara
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065733/
https://ncbi.nlm.nih.gov/pubmed/33810393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11040278
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