Engineering G-quadruplex aptamer to modulate its binding specificity

The use of aptamers in bioanalytical and biomedical applications exploits their ability to recognize cell surface protein receptors. Targeted therapeutics and theranostics come to mind in this regard. However, protein receptors occur on both cancer and normal cells; as such, aptamers are now taxed w...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Natl Sci Rev
Autori principali: Li, Long, Xu, Shujuan, Peng, Xueyu, Ji, Yuzhuo, Yan, He, Cui, Cheng, Li, Xiaowei, Pan, Xiaoshu, Yang, Lu, Qiu, Liping, Jiang, Jianhui, Tan, Weihong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065617/
https://ncbi.nlm.nih.gov/pubmed/33936748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwaa202
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