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Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity
Guanine-rich nucleic acids can form G-quadruplexes that are important in gene regulation, biosensor design and nano-structure construction. In this article, we report on the development of a nanopore encapsulating single-molecule method for exploring how cations regulate the folding and unfolding of...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647319/ https://ncbi.nlm.nih.gov/pubmed/19112078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn968 |
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