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Single-molecule detection of folding and unfolding of the G-quadruplex aptamer in a nanopore nanocavity

Guanine-rich nucleic acids can form G-quadruplexes that are important in gene regulation, biosensor design and nano-structure construction. In this article, we report on the development of a nanopore encapsulating single-molecule method for exploring how cations regulate the folding and unfolding of...

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Detalles Bibliográficos
Main Authors: Shim, Ji Wook, Tan, Qiulin, Gu, Li-Qun
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647319/
https://ncbi.nlm.nih.gov/pubmed/19112078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn968
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