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Encapsulating a Single G-Quadruplex Aptamer in a Protein Nanocavity
The α-hemolysin (αHL) protein pore has many applications in biotechnology. This article describes a single-molecule manipulation system that utilizes the nanocavity enclosed by this pore to non-covalently encapsulate a guest molecule. The guest is the thrombin-binding aptamer (TBA) that folds into t...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2657931/ https://ncbi.nlm.nih.gov/pubmed/18563930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp0775911 |
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