Engineering G-quadruplex aptamer to modulate its binding specificity

The use of aptamers in bioanalytical and biomedical applications exploits their ability to recognize cell surface protein receptors. Targeted therapeutics and theranostics come to mind in this regard. However, protein receptors occur on both cancer and normal cells; as such, aptamers are now taxed w...

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Podrobná bibliografie
Vydáno v:Natl Sci Rev
Hlavní autoři: Li, Long, Xu, Shujuan, Peng, Xueyu, Ji, Yuzhuo, Yan, He, Cui, Cheng, Li, Xiaowei, Pan, Xiaoshu, Yang, Lu, Qiu, Liping, Jiang, Jianhui, Tan, Weihong
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065617/
https://ncbi.nlm.nih.gov/pubmed/33936748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwaa202
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