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Engineering G-quadruplex aptamer to modulate its binding specificity

The use of aptamers in bioanalytical and biomedical applications exploits their ability to recognize cell surface protein receptors. Targeted therapeutics and theranostics come to mind in this regard. However, protein receptors occur on both cancer and normal cells; as such, aptamers are now taxed w...

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Detalhes bibliográficos
Publicado no:Natl Sci Rev
Main Authors: Li, Long, Xu, Shujuan, Peng, Xueyu, Ji, Yuzhuo, Yan, He, Cui, Cheng, Li, Xiaowei, Pan, Xiaoshu, Yang, Lu, Qiu, Liping, Jiang, Jianhui, Tan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065617/
https://ncbi.nlm.nih.gov/pubmed/33936748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwaa202
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