BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice

In this study, we using the in vivo destabilization of the medial meniscus (DMM) mouse model to investigate the role of bone morphogenetic protein 5 (BMP5) in osteoarthritis (OA) progression mediated via chondrocyte senescence and apoptosis. BMP5 expression was significantly higher in knee articular...

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Библиографические подробности
Опубликовано в: :Aging (Albany NY)
Главные авторы: Shao, Yan, Zhao, Chang, Pan, Jianying, Zeng, Chun, Zhang, Hongbo, Liu, Liangliang, Fan, Kai, Liu, Xin, Luo, Bingsheng, Fang, Hang, Bai, Xiaochun, Zhang, Haiyan, Cai, Daozhang
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals 2021
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064147/
https://ncbi.nlm.nih.gov/pubmed/33744859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202708
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