Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

BACKGROUND: To investigate the role and regulatory mechanisms of fargesin, one of the main components of Magnolia fargesii, in macrophage reprogramming and crosstalk across cartilage and synovium during osteoarthritis (OA) development. METHODS: Ten-week-old male C57BL/6 mice were randomized and assi...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Lu, Jiansen, Zhang, Hongbo, Pan, Jianying, Hu, Zhiqiang, Liu, Liangliang, Liu, Yanli, Yu, Xiao, Bai, Xiaochun, Cai, Daozhang, Zhang, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120707/
https://ncbi.nlm.nih.gov/pubmed/33990219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02512-z
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