Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARγ to inhibit NF‐κB signalling pathway

Synovial macrophage polarization and inflammation are essential for osteoarthritis (OA) development, yet the molecular mechanisms and regulation responsible for the pathogenesis are still poorly understood. Here, we report that pseudolaric acid B (PAB) attenuated articular cartilage degeneration and...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Lu, Jiansen, Guan, Hong, Wu, Dan, Hu, Zhiqiang, Zhang, Hongbo, Jiang, Huaji, Yu, Jingyao, Zeng, Ke, Li, Hongyu, Zhang, Haiyan, Pan, Chenglong, Cai, Daozhang, Yu, Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278075/
https://ncbi.nlm.nih.gov/pubmed/34117708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16670
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