BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice

In this study, we using the in vivo destabilization of the medial meniscus (DMM) mouse model to investigate the role of bone morphogenetic protein 5 (BMP5) in osteoarthritis (OA) progression mediated via chondrocyte senescence and apoptosis. BMP5 expression was significantly higher in knee articular...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Shao, Yan, Zhao, Chang, Pan, Jianying, Zeng, Chun, Zhang, Hongbo, Liu, Liangliang, Fan, Kai, Liu, Xin, Luo, Bingsheng, Fang, Hang, Bai, Xiaochun, Zhang, Haiyan, Cai, Daozhang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064147/
https://ncbi.nlm.nih.gov/pubmed/33744859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202708
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