BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice

In this study, we using the in vivo destabilization of the medial meniscus (DMM) mouse model to investigate the role of bone morphogenetic protein 5 (BMP5) in osteoarthritis (OA) progression mediated via chondrocyte senescence and apoptosis. BMP5 expression was significantly higher in knee articular...

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Enregistré dans:
Détails bibliographiques
Publié dans:Aging (Albany NY)
Auteurs principaux: Shao, Yan, Zhao, Chang, Pan, Jianying, Zeng, Chun, Zhang, Hongbo, Liu, Liangliang, Fan, Kai, Liu, Xin, Luo, Bingsheng, Fang, Hang, Bai, Xiaochun, Zhang, Haiyan, Cai, Daozhang
Format: Artigo
Langue:Inglês
Publié: Impact Journals 2021
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064147/
https://ncbi.nlm.nih.gov/pubmed/33744859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202708
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