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Temperature Based Process Characterization of Pharmaceutical Freeze-Thaw Operations
In biopharmaceutical production processes, freeze-thaw operations are used to ensure product integrity during long hold times, but they also introduce additional stresses such as freeze concentration gradients that might lead to a loss of protein activity. Process characterization of freeze-thaw ope...
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| Veröffentlicht in: | Front Bioeng Biotechnol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8062970/ https://ncbi.nlm.nih.gov/pubmed/33898399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.617770 |
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