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Freeze–thaw characterization process to minimize aggregation and enable drug product manufacturing of protein based therapeutics
Physical instabilities of proteins in the form of protein aggregation continue to be a major challenge in the development of protein drug candidates. Aggregation can occur during different stages of product lifecycle such as freeze–thaw, manufacturing, shipping, and storage, and can potentially dela...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8166975/ https://ncbi.nlm.nih.gov/pubmed/34059716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90772-9 |
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