Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice

OBJECTIVE: Cytoskeletal structural proteins maintain cell structural integrity by bridging extracellular matrix (ECM) with contractile filaments. During AAA development, (i) aortic medial degeneration is associated with loss of smooth muscle cell (SMC) integrity, and (ii) fibrogenic mesenchymal cell...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Muniappan, Latha, Okuyama, Michihiro, Javidan, Aida, Thiagarajan, Devi, Jiang, Weihua, Moorleghen, Jessica J., Yang, Lihua, Balakrishnan, Anju, Howatt, Deborah A., Uchida, Haruhito A., Saido, Takaomi C., Subramanian, Venkateswaran
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062307/
https://ncbi.nlm.nih.gov/pubmed/33761765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315546
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