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Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice

Adipose tissue macrophages have been proposed as a link between obesity and insulin resistance. However, the mechanisms underlying these processes are not completely defined. Calpains are calcium-dependent neutral cysteine proteases that modulate cellular function and have been implicated in various...

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Publicado no:Sci Rep
Main Authors: Muniappan, Latha, Javidan, Aida, Jiang, Weihua, Mohammadmoradi, Shayan, Moorleghen, Jessica J., Katz, Wendy S., Balakrishnan, Anju, Howatt, Deborah A., Subramanian, Venkateswaran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663911/
https://ncbi.nlm.nih.gov/pubmed/29089532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14719-9
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