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Potent sialic acid inhibitors that target influenza A virus hemagglutinin

Eradicating influenza A virus (IAV) is difficult, due to its genetic drift and reassortment ability. As the infectious cycle is initiated by the influenza glycoprotein, hemagglutinin (HA), which mediates the binding of virions to terminal sialic acids moieties, HA is a tempting target of anti-influe...

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Publicado en:Sci Rep
Autores principales: Chang, Yu-Jen, Yeh, Cheng-Yun, Cheng, Ju-Chien, Huang, Yu-Qi, Hsu, Kai-Cheng, Lin, Yu-Feng, Lu, Chih-Hao
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060387/
https://ncbi.nlm.nih.gov/pubmed/33883588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87845-0
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