Force Spectroscopy Shows Dynamic Binding of Influenza Hemagglutinin and Neuraminidase to Sialic Acid

The influenza A virus infects target cells through multivalent interactions of its major spike proteins, hemagglutinin (HA) and neuraminidase (NA), with the cellular receptor sialic acid (SA). HA is known to mediate the attachment of the virion to the cell, whereas NA enables the release of newly fo...

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Publicat a:Biophys J
Autors principals: Reiter-Scherer, Valentin, Cuellar-Camacho, Jose Luis, Bhatia, Sumati, Haag, Rainer, Herrmann, Andreas, Lauster, Daniel, Rabe, Jürgen P.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428919/
https://ncbi.nlm.nih.gov/pubmed/30799074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.041
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