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Force Spectroscopy Shows Dynamic Binding of Influenza Hemagglutinin and Neuraminidase to Sialic Acid

The influenza A virus infects target cells through multivalent interactions of its major spike proteins, hemagglutinin (HA) and neuraminidase (NA), with the cellular receptor sialic acid (SA). HA is known to mediate the attachment of the virion to the cell, whereas NA enables the release of newly fo...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Reiter-Scherer, Valentin, Cuellar-Camacho, Jose Luis, Bhatia, Sumati, Haag, Rainer, Herrmann, Andreas, Lauster, Daniel, Rabe, Jürgen P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428919/
https://ncbi.nlm.nih.gov/pubmed/30799074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.01.041
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