Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions

Sialic acids (Sia) are the primary receptors for influenza viruses and are widely displayed on cell surfaces and in secreted mucus. Sia may be present in variant forms that include O-acetyl modifications at C-4, C-7, C-8, and C-9 positions and N-acetyl or N-glycolyl at C-5. They can also vary in the...

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發表在:J Virol
Main Authors: Barnard, Karen N., Alford-Lawrence, Brynn K., Buchholz, David W., Wasik, Brian R., LaClair, Justin R., Yu, Hai, Honce, Rebekah, Ruhl, Stefan, Pajic, Petar, Daugherity, Erin K., Chen, Xi, Schultz-Cherry, Stacey L., Aguilar, Hector C., Varki, Ajit, Parrish, Colin R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
主題:
Virus-Cell Interactions
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163148/
https://ncbi.nlm.nih.gov/pubmed/32051275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01567-19
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