Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions

Sialic acids (Sia) are the primary receptors for influenza viruses and are widely displayed on cell surfaces and in secreted mucus. Sia may be present in variant forms that include O-acetyl modifications at C-4, C-7, C-8, and C-9 positions and N-acetyl or N-glycolyl at C-5. They can also vary in the...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Barnard, Karen N., Alford-Lawrence, Brynn K., Buchholz, David W., Wasik, Brian R., LaClair, Justin R., Yu, Hai, Honce, Rebekah, Ruhl, Stefan, Pajic, Petar, Daugherity, Erin K., Chen, Xi, Schultz-Cherry, Stacey L., Aguilar, Hector C., Varki, Ajit, Parrish, Colin R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163148/
https://ncbi.nlm.nih.gov/pubmed/32051275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01567-19
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