Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions

Sialic acids (Sia) are the primary receptors for influenza viruses and are widely displayed on cell surfaces and in secreted mucus. Sia may be present in variant forms that include O-acetyl modifications at C-4, C-7, C-8, and C-9 positions and N-acetyl or N-glycolyl at C-5. They can also vary in the...

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Udgivet i:J Virol
Main Authors: Barnard, Karen N., Alford-Lawrence, Brynn K., Buchholz, David W., Wasik, Brian R., LaClair, Justin R., Yu, Hai, Honce, Rebekah, Ruhl, Stefan, Pajic, Petar, Daugherity, Erin K., Chen, Xi, Schultz-Cherry, Stacey L., Aguilar, Hector C., Varki, Ajit, Parrish, Colin R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7163148/
https://ncbi.nlm.nih.gov/pubmed/32051275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01567-19
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