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Potent sialic acid inhibitors that target influenza A virus hemagglutinin

Eradicating influenza A virus (IAV) is difficult, due to its genetic drift and reassortment ability. As the infectious cycle is initiated by the influenza glycoprotein, hemagglutinin (HA), which mediates the binding of virions to terminal sialic acids moieties, HA is a tempting target of anti-influe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chang, Yu-Jen, Yeh, Cheng-Yun, Cheng, Ju-Chien, Huang, Yu-Qi, Hsu, Kai-Cheng, Lin, Yu-Feng, Lu, Chih-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060387/
https://ncbi.nlm.nih.gov/pubmed/33883588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87845-0
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