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Potent sialic acid inhibitors that target influenza A virus hemagglutinin

Eradicating influenza A virus (IAV) is difficult, due to its genetic drift and reassortment ability. As the infectious cycle is initiated by the influenza glycoprotein, hemagglutinin (HA), which mediates the binding of virions to terminal sialic acids moieties, HA is a tempting target of anti-influe...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chang, Yu-Jen, Yeh, Cheng-Yun, Cheng, Ju-Chien, Huang, Yu-Qi, Hsu, Kai-Cheng, Lin, Yu-Feng, Lu, Chih-Hao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060387/
https://ncbi.nlm.nih.gov/pubmed/33883588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87845-0
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