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Design and Structure–Activity Relationship of a Potent Furin Inhibitor Derived from Influenza Hemagglutinin

[Image: see text] Furin plays an important role in various pathological states, especially in bacterial and viral infections. A detailed understanding of the structural requirements for inhibitors targeting this enzyme is crucial to develop new therapeutic strategies in infectious diseases, includin...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Lewandowska-Goch, Monika A., Kwiatkowska, Anna, Łepek, Teresa, Ly, Kévin, Navals, Pauline, Gagnon, Hugo, Dory, Yves L., Prahl, Adam, Day, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957945/
https://ncbi.nlm.nih.gov/pubmed/33738063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00386
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