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Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

Many viruses have membrane glycoproteins that are activated at cleavage sites containing multiple arginine and lysine residues by cellular proteases so far not identified. The proteases responsible for cleavage of the hemagglutinin of fowl plague virus, a prototype of these glycoproteins, has now be...

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Autores principales: Stieneke-Gröber, A, Vey, M, Angliker, H, Shaw, E, Thomas, G, Roberts, C, Klenk, H D, Garten, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC556715/
https://ncbi.nlm.nih.gov/pubmed/1628614
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