XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

Single-cell RNA sequencing (scRNA-seq) of tissues has revealed remarkable heterogeneity of cell types and states but does not provide information on the spatial organization of cells. To better understand how individual cells function within an anatomical space, we developed XYZeq, a workflow that e...

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Publicat a:Sci Adv
Autors principals: Lee, Youjin, Bogdanoff, Derek, Wang, Yutong, Hartoularos, George C., Woo, Jonathan M., Mowery, Cody T., Nisonoff, Hunter M., Lee, David S., Sun, Yang, Lee, James, Mehdizadeh, Sadaf, Cantlon, Joshua, Shifrut, Eric, Ngyuen, David N., Roth, Theodore L., Song, Yun S., Marson, Alexander, Chow, Eric D., Ye, Chun Jimmie
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8059935/
https://ncbi.nlm.nih.gov/pubmed/33883145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg4755
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