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Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective

The tumor microenvironment (TME) comprises complex interactions of multiple cell types that determines cell behavior and metabolism such as nutrient competition and immune suppression. We discuss the various types of heterogeneity that exist in solid tumors, and the complications this invokes for st...

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Bibliographic Details
Published in:Metabolites
Main Authors: Fan, Teresa W. -M., Higashi, Richard M., Chernayavskaya, Yelena, Lane, Andrew N.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345423/
https://ncbi.nlm.nih.gov/pubmed/32549391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10060249
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