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Resolving Metabolic Heterogeneity in Experimental Models of the Tumor Microenvironment from a Stable Isotope Resolved Metabolomics Perspective

The tumor microenvironment (TME) comprises complex interactions of multiple cell types that determines cell behavior and metabolism such as nutrient competition and immune suppression. We discuss the various types of heterogeneity that exist in solid tumors, and the complications this invokes for st...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Fan, Teresa W. -M., Higashi, Richard M., Chernayavskaya, Yelena, Lane, Andrew N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7345423/
https://ncbi.nlm.nih.gov/pubmed/32549391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10060249
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