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Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis
Cancer patients with liver metastasis demonstrate significantly worse outcomes than those without liver metastasis when treated with anti-PD-1 immunotherapy. The mechanism of liver metastases-induced reduction in systemic antitumor immunity is unclear. Using a dual-tumor immunocompetent mouse model,...
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| 發表在: | Sci Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7755924/ https://ncbi.nlm.nih.gov/pubmed/33008914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aba0759 |
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